Crossing paths: UNAM and the Nobel Prize in Chemistry

Two decades ago, in a UNAM laboratory, young researcher Daniel Adriano Silva Manzano had a moment that would change his life forever.

A graduate of UNAM’s School of Medicine with a degree in Basic Biomedical Research and a Ph.D. in Biochemical Sciences, he never anticipated how a single lecture would shape the course of his career.

David Baker, recently awarded the Nobel Prize in Chemistry for his groundbreaking work in computational protein design, had arrived at Ciudad Universitaria to deliver a presentation. Despite being encouraged to visit the campus’s architectural landmarks, Baker chose instead to spend time in the laboratories, his natural habitat.

By chance, Silva Manzano was the only student present in the laboratory Baker chose to visit. Fascinated by Daniel’s research, the American scientist engaged in hours of discussion with him. This encounter sparked in Silva an unwavering ambition: to collaborate with Baker.

Over the years, Daniel pursued a challenging academic path but eventually achieved his goal. For the past decade, he has been an integral member of Baker’s research team.

”Being part of a team on the verge of receiving a Nobel Prize is both exhilarating and somewhat daunting. We had a feeling this would be Baker’s year—it’s the recognition he’s long deserved. I set my alarm to watch the announcement live and felt immense pride for him and everyone who contributed to this project. This award not only celebrates his work but also brings visibility to all researchers dedicated to protein science,” Daniel shared with enthusiasm.